For US Audiences Only: The Medicines Company to Announce Fourth Quarter and Full Year 2009 Financial Results on Wednesday, February 17, 2010

Conference Call to Be Held at 8:30 a.m. Eastern Time

PARSIPPANY, NJ--(Marketwire - February 9, 2010) - The Medicines Company (NASDAQ: MDCO) has scheduled its quarterly conference call for Wednesday, February 17, 2010 at 8:30 a.m. Eastern Time to discuss fourth quarter and full year 2009 financial results, operational developments, and outlook for 2010.

The conference call will be available via phone and webcast. The dial in information is listed below:

Domestic Dial In:                   800.599.9829
International Dial In:              617.847.8703
Passcode for both dial in numbers:  95981334

Replay is available from 11:30 a.m. Eastern Time following the conference call through February 24, 2010. To hear a replay of the call dial 888-286-8010 (domestic) and 617-801-6888 (international). Passcode for both dial in numbers is 99158077.

This call is being webcast and can be accessed at The Medicines Company website at www.themedicinescompany.com.

About The Medicines Company

The Medicines Company (NASDAQ: MDCO) is focused on advancing the treatment of critical care patients through the delivery of innovative, cost-effective medicines to the worldwide hospital marketplace. The Company markets Angiomax® (bivalirudin) in the United States and other countries for use in patients undergoing coronary angioplasty, and Cleviprex® (clevidipine butyrate) injectable emulsion in the United States for the reduction of blood pressure when oral therapy is not feasible or not desirable. The Company's website is www.themedicinescompany.com.

Contact: Andreas Bremer Senior Vice President and Chief Business Officer 011 41 43 813 3335 investor.relations@themedco.com